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Liver Cancer in Dogs

Two types of liver cancer in dogs can arise - Primary liver cancer and metastatic liver cancer.

Primary Liver Cancer

Liver Cancer in Dogs

Primary liver cancer is the result of a primary liver tumor (one that originates in the liver). The most common primary liver tumor is the hepatocellular carcinoma which usually does not spread to other parts of the body. Instead, the tumor invades into the liver tissue.

Primary liver cancer is less common than metastatic liver cancer in dogs. Primary liver cancer occurs more frequently in older dogs (10 years of age or older). There is a slightly increased risk of primary liver tumors in male dogs. Although rather rare, primary liver cancer in dogs can also metastasize to other parts of the body.

Metastatic Liver Cancer

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Metastatic, or secondary, liver cancer is one that has spread to the liver from other organs. Metastatic liver tumors are generally multiple nodules.

The liver is the largest organ in the dog's body, and it is involved in a large number of bodily functions and processes. In particular, the liver is one of the main organs responsible for detoxifying many toxic substances circulating in the body. It is understandable, therefore, that the liver is one of the primary targets of almost all metastatic cancers. Cancer that metastasizes tends to travel to the liver through the blood stream or the lymphatic system, and the fact that the liver is supplied blood through two blood vessels instead of one makes it all the more vulnerable.

Signs of Liver Cancer in Dogs

In the early stage of canine liver cancer, clinical signs are vague and not distinctive. As the disease progresses, some symptoms of canine liver cancer include:

  • Vomiting
  • Appetite loss
  • Weight loss
  • Lethargy
  • Blood in stools (a sign of internal bleeding)
  • Excessive thirst and urination
  • Pale gums (a sign of anemia)
  • Anemia as a result of appetite loss and/or internal bleeding
  • Jaundice as a result of liver disease and anemia

As you can see, quite a few other diseases, especially diseases that involve the liver, may cause the same signs as listed above. Other common liver diseases that may cause similar symptoms include hepatitis, leptospirosis (an infectious liver disease in dogs caused by a kind of bacteria called a spirochete), viral and fungal infections of the liver, etc.

Due to a lack of distinctive symptoms in the early stage and the fact that the liver can continue to function for a while even having been afflicted by cancer, most liver cancer cases are diagnosed rather late, resulting in a poor prognosis. (See this page for an example of how vague the symptoms are and how fast a dog can succcumb to liver cancer at its later stage.)

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Causes of Liver Cancer in Dogs

The cause of primary liver cancer may be related to environmental factors, such as exposure to cancer-causing chemicals (carcinogens). Examples of possible carcinogens include chemicals in some commercial pet food (food additives, artificial coloring and flavors), certain pesticides, dyes, etc.

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Diagnosis of Liver Cancer in Dogs

If canine liver cancer is suspected, usually the following tests will be done:

  • Complete blood count
  • Biochemical profile
  • Abdominal and chest x-rays
  • Abdominal ultrasound
  • Clotting tests
  • Urinalysis
  • Liver biopsy

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Treatment for Liver Cancer in Dogs

Canine Liver Cancer

For primary cancer cases that show no evidence of metastatic disease, surgical removal of the liver tumor may be possible. If complete removal of the cancerous cells can be achieved, the dog patient can live for at least one year or so after surgery. Some may even survive for several years.

Malignant tumors that cannot be surgically removed due to severe involvement of the liver and/or metastatic spread to other parts of the body carry a very poor prognosis.

In cases of secondary liver cancer, chemotherapy is sometimes recommended. (Chemotherapy has not been shown to be useful for treating primary malignant liver tumors, which are highly resistant to chemotherapy drugs.)

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Natural Remedies for Liver Cancer in Dogs

Although natural remedies such as herbs, homeopathic remedies, and natural supplements may not be able to destroy tumors, they are nonetheless effective in strengthening the immune system, making the body stronger to fight against diseases such as cancer.

Some dog parents have reported success in using the herbal formula "Essiac" to treat canine cancer, while others swear by such remedies as the "Budwig Diet". For more information on these and other natural remedies for canine cancer, please visit our pages on Herbs for Cancer in Dogs and Dog Cancer Diet.



Related Topics

Dog Cancer
Symptoms of Dog Cancer
Conventional Cancer Treatment for Dog Patients
Herbs for Cancer in Dogs
Dog Cancer Diet

References

S. Messonnier, The Natural Vet's Guide to Preventing and Treating Cancer in Dogs (New World Library, 2006).
A.D. Shojai, New Choices in Natural Healing for Dogs and Cats (Rodale Press, Inc., 1999).


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