Liver Shunt in Dogs

This page focuses on the topic of canine liver shunt (portosystemic shunting). In particular, it looks at this problem's symptoms, possible causes, diagnosis and treatment. It also discusses how to use natural remedies such as herbs to help dogs with liver problems.

"Portosystemic shunting" (PSS) or liver shunt is a condition in which the blood-flow to and from the dog's liver has been compromised. Specifically, canine liver shunt causes blood to flow around the liver, not through it, resulting in blood bypassing the liver.


Two Types of Liver Shunt in Dogs

Canine liver shunts can be congenital which is a birth defect, or acquired which may be the result of severe liver disease such as cirrhosis. Congenital shunts are more common in dogs than acquired shunts.

Information on Canine Liver Shunts

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Development of Congenital Liver Shunt in Dogs

Beagle Puppy Congenital liver shunt in dogs can be "intrahepatic shunt" ("inside the liver") or "extrahepatic shunt" ("outside the liver"). Both of these conditions are formed while the puppy's body is developing inside the mother.

When a dog fetus is developing inside the mother's uterus, it requires the help of the mother's liver for liver functions, such as detoxification, protein production, and storage of glucose. Dog fetuses do not have a functional liver until the end of gestation. Toward the beginning of gestation, there is a "naturally-occurring" liver shunt (a blood vessel called "ductus venosus") that delivers blood through the dog's liver directly to the heart.

In normal circumstances, the large liver shunt (ductus venosus) closes down shortly before birth so that the puppy can be born with a fully functional liver that works on its own. When the shunt does not seal closed when the puppy is born, the puppy is said to have an "intrahepatic shunt".

An "extrahepatic shunt" occurs when there is a genetic abnormaly in which the blood flowing to the liver is re-routed around the liver instead of the blood going through the liver. This also occurs in-vitro when the puppy fetus is developing inside the mother.

Who are At Risk?

If a puppy has a congenital liver shunt, most commonly he will some signs by six months of age. However, shunts have been diagnosed in adults as old as 10 years. Female dogs are more susceptible to shunts than males.

Breed-wise, small breed dogs tend to have extrahepatic shunts; for example: Yorkshire terriers, schnauzers, maltese, dachshunds, Jack Russell terriers, shih tzus, poodles, to name a few. Large breed dogs tend to have intrahepatic shunts and breeds that are predisposed include Irish wolfhounds, Labrador retrievers, Australian shepherds, Australian cattle dogs, and old English sheepdogs.

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Signs and Symptoms of Liver Shunt in Dogs

If a dog is suffering from a liver shunt, he lacks the necessary materials (particularly protein) to give him a ready source of energy and to help him grow. This causes the dog to be smaller and weaker than normal.

Also, the liver is unable to properly get rid of all the toxins, causing toxin buildup in the bloodstream or kidneys. Toxin buildup often causes seizures in dogs.

In addition, a dog with a liver shunt may also show the following symptoms:

  • Lack of appetite, resulting in weight loss
  • Lethargy and general weakness
  • Behavioral abnormalities (e.g. circling, stumbling, disorientation, unresponsiveness, staring into space, head pressing against objects)

There are other less common signs, such as:

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Diagnosis and Conventional Treatment

Initial diagnosis is through blood work. Blood urea nitrogen (BUN) and albumin concentrations in dogs with congenital liver shunts are usually low. Liver enzymes such as ALT and AST can be elevated. Another key indication of liver shunts is extremely high blood bile acid concentrations (Normal bile acid concentration is about 20 whereas a dog with a liver shunt can have a concentration of over 100).

However, these are not enough for a definitive diagnosis. The only definitive way to tell if your dog has a liver shunt and the only way to tell if it is an "intrahepatic" or "extrahepatic shunt" would be by some extra diagnostics, such as Cat scan ("CT"), MRI, ultrasound, or exploratory surgery.

Extrahepatic shunts can be corrected by surgery relatively easily. Intrahepatic shunts, on the other hand, have a poorer prognosis and are more difficult to be surgically fixed. Dogs with intrahepatic shunts tend to have post-surgical secondary complications.

Natural Remedies That May Help

If your dog has been diagnosed with a liver shunt, but is otherwise acting fine, then there are several things that you can do to manage your dog's liver shunt problem. Natural remedies such as herbs and antioxidant supplements can be used to help liver functions such as detoxification. Homeopathic remedies can also help the body detoxify itself. Please visit this page for more information.

Finally, you may also want to work with a pet nutritionist to manage your dog's liver shunt through nutritional therapy. The liver is the organ that processes protein and, since dogs with liver shunts have impaired liver functions, they should be fed a reduced amount of protein. However, the protein fed to a dog with a liver shunt has to be of excellent quality - human-grade organic meat is best. Consult with a pet nutritionist to design a home-made reduced-protein diet that is nutritionally balanced for your dog.

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